HORDB

General Information

ID: hor002485
Uniprot ID: NA
Protein name: GSPYFVamide
Gene name: NA
Organism: Helix pomatia
Family: NA
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: GSPYFV
Length: 6
Propeptide: NA
Signal peptide: NA
Modification: T6 Valine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Evoked a concentration dependent decrease of basal tension of the denervated muscle
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002485_AF2.pdb

hor002485_ESM.pdb

Physical Information

Mass:	75810	Formula:	C33H44N6O9
Absent amino acids:	ACDEHIKLMNQRTW	Common amino acids:	FGPSVY
pI:	6.09	Basic residues:	0
Polar residues:	3	Hydrophobic residues:	2
Hydrophobicity:	48.33	Boman Index:	442
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	48.33
Instability Index:	8156.67	Extinction Coefficient cystines:	1490
Absorbance 280nm:	298

Literature

PubMed ID: 20307609
Title: Peptidergic Modulation of Serotonin and Nerve Elicited Responses of the Salivary Duct Muscle in the Snail, Helix Pomatia